Papaya (Carica papaya L.) belongs to the family caricaceae and is one of the most well researched plants. It is used widely due to its medicinal properties. The present study was carried out to find out the susceptibility of Mycobacterium tuberculosis to ethanolic extract of leaves and seeds of Carica papaya. By using alamar blue dye assay and in-vitro bioassay based on inactivation of viability by a procedure similar to neutralization test were used to study the inhibition of Mycobacterium tuberculosis which shows anti-tb activity against clinical strains of sensitive and drug resistant Mycobacterium tuberculosis (pyrazinamide, streptomycin, ciprofloxacin). The present results are possibly one of the first few investigations showing a clear indication of the potent anti-tubercular effect of carica papaya.
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